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Abiquin Hydroquinone, Tretinoin & Fluocinolone Cream 15g
Abiquin Cream (Hydroquinone Tretinoin And Fluocinolone) is prescribed for the short-term treatment of moderate to severe facial melasma. Patients should avoid sun exposure while using this cream and apply a broad-spectrum sunscreen with at least SPF 30.
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✅ Description:
Abiquin Cream combines three active agents—Fluocinolone Acetonide, Hydroquinone, and Tretinoin—which are commonly used in the management of melasma.
- Fluocinolone Acetonide is a topical corticosteroid that helps reduce inflammation.
- Hydroquinone is a skin-lightening agent that interferes with melanin production by inhibiting the tyrosine-tyrosinase pathway.
- Tretinoin is a keratolytic that promotes skin cell turnover.
Though the exact mechanism by which the combination works against melasma is not fully understood, the synergistic action of these components provides a therapeutic benefit.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Dosage & Administration
- Apply once daily at night, at least 30 minutes before bedtime.
- Cleanse the face and neck with a gentle cleanser, rinse, and pat dry.
- Apply a thin layer to the melasma-affected areas, extending about half an inch onto the surrounding normal skin. Gently massage the cream into the skin.
- During daytime, apply sunscreen and wear protective clothing. Limit sun exposure.
- Moisturizers and makeup may be used during the day.
Pediatric Use: Safety and efficacy in children have not been established.
✔️ Side Effects
Some users may experience:
- Mild to moderate redness, dryness, peeling, burning, or itching at the site of application
- Rarely, severe allergic reactions such as difficulty breathing or asthma exacerbation
✔️ Avoid using:
- Abrasive or medicated soaps
- Products with alcohol or strong astringents
- Drying cosmetics
- Keratolytic products or other irritants
- Other topical or systemic agents that cause photosensitivity
✔️ Contraindications
Do not use in patients with known hypersensitivity to Fluocinolone Acetonide, Hydroquinone, Tretinoin, or any ingredient in the formulation.
✔️ Pregnancy & Lactation
Pregnancy:
- Category C. Contains tretinoin, which has been linked to fetal harm in animal studies.
- Should only be used in pregnancy if the expected benefits outweigh potential risks.
Lactation:
- While it’s unclear if topical use leads to significant drug levels in breast milk, systemic corticosteroids can appear in breast milk.
- Caution is advised when used by breastfeeding mothers.
✔️ Precautions & Warnings
- Irritation from Hydroquinone and Tretinoin may occur; this includes redness, itching, dryness, and mild burning.
- If severe irritation or allergic reaction occurs, discontinue use.
- Contains Fluocinolone Acetonide, which can be absorbed through the skin and may lead to reversible suppression of the HPA axis, potentially causing Cushing's syndrome, high blood sugar, or glucosuria.
- Discontinue use if systemic effects are observed; normal HPA axis function typically returns after stopping the cream.
✔️ Storage:
Store in a cool, dry place away from light. Do not freeze. Keep out of children’s reach.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
